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James H. Stein, MD's avatar

A brief note to readers. Thanks to everyone who has taken the time to read and comment. As you can see from my previous comments here, I welcome substantive disagreement, including critiques that challenge my assumptions or conclusions. That kind of engagement is helpful and interesting to me and to this Substack community.

To clarify, this post was not an argument about incumbents versus new paradigms, nor a defense of professional authority. It was an exploration of epistemology - specifically, how medical knowledge is framed, bounded, and communicated under conditions of uncertainty, and the responsibilities that come with speaking authoritatively to large audiences. The focus was a disagreement about how to characterize the limits of knowledge claimed by a single podcaster, Peter Attia. I explore these themes in more detail in a recently published JAMA Cardiology commentary (https://jamanetwork.com/journals/jamacardiology/fullarticle/2840914) and in this related Substack post, Physician, Podcaster, and Patient: A New Health Triangle (https://jamesstein18.substack.com/p/physician-podcaster-and-patient-a)

I’m less interested in responses that recast my arguments into something they weren’t or that shift the discussion away from epistemological questions toward identity-based or performative conflict aimed at driving engagement. In some online spaces, disagreement functions less as an effort to examine a claim and more as a way to signal alignment. That’s not the conversation I’m trying to have here. Thank you - Jim

PS. I hope this can remain a snark-free zone, free of eye-rolling, name-calling, or speculation about incentives. This isn’t X.

Dr R's avatar

I will take Peter Attia’s advice any day over what many Dr’s traffic in which is waiting until I’m sick to pay any attention to me. I’ve had to push Dr to start statin therapy when by the guidelines I’m a candidate. No Dr ever told me to lose weight and exercise when I clearly needed to. Sarcopenia? Silence. Stop drinking? Crickets. Attia at least makes it clear what the tradeoffs are. Nothing in his book is harmful. So tired of all the critics without a better alternative.

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